Title :
Knowledge Discovery Scientific Workflows in Clinico-Genomics
Author :
Potamias, George ; Koumakis, Lefteris ; Kanterakis, Alexandros ; Sfakianakis, Stelios ; Analyti, Anastasia ; Moustakis, Vassilis ; Kafetzopoulos, Dimitris ; Rueping, Stefan ; Tsiknakis, Manolis
Author_Institution :
Found. for Res. & Technol., Hellas (FORTH), Heraklion
Abstract :
With the completion of the human genome and the entrance into the post-genomic era, translational research rises as a major need. In this paper, we present a knowledge discovery workflow (KDw) and its utilization in the context of clinico-genomic trials. KDw aims towards the discovery of ´evidential´ correlations between patients´ genomic and clinical profiles. Application of KDw on a real-world clinico-genomic (breast cancer) study demonstrates the reliability, efficacy, and efficiency of the approach.
Keywords :
data mining; genetics; medical computing; medical information systems; clinico-genomics trial; knowledge discovery scientific workflow; patient genome; Bioinformatics; Data mining; Diseases; Genomics; Laboratories; Management information systems; Mediation; Medical diagnostic imaging; Medical treatment; Risk management;
Conference_Titel :
Tools with Artificial Intelligence, 2007. ICTAI 2007. 19th IEEE International Conference on
Conference_Location :
Patras
Print_ISBN :
978-0-7695-3015-4
DOI :
10.1109/ICTAI.2007.32
