MR-Compatible blood sampler for PET

Author

Breuer, J. ; Grazioso, R. ; Corbeil, J. ; Zhang, N. ; Schmand, M. ; Wienhard, K.

Author_Institution

Max-Planck-Inst. for Neurological Res., Cologne

Volume

5

fYear

2007

fDate

Oct. 26 2007-Nov. 3 2007

Firstpage

3426

Lastpage

3429

Abstract

An MR-compatible automatic blood sampler prototype for quantifying radioactivity in blood has been built and tested. The determination of the so-called input function is necessary to investigate the kinetics of the administered radiotracer in PET studies. The counting detector consists of 2 coincident LSO blocks (50times40times 30 mm³) coupled each to a single APD (10 times 10 mm² active area). Preliminary experimental and numerical results indicate that a specific sensitivity of about 1 cps / (nCi / ml) can be achieved. Tests during bimodal simultaneous MR/PET scans will be carried out in the future with a Siemens 3 T-Trio MR scanner and a brain PET insert.

Keywords

biomedical MRI; brain; positron emission tomography; 3T-Trio MR scanner; MR-compatible blood sampler; bimodal simultaneous MR-PET scans; brain PET insert; magnetic resonance imaging; radioactivity; radiotracer; Biomedical imaging; Blood; Catheters; Filters; Kinetic theory; Molecular imaging; Photonic crystals; Positron emission tomography; Prototypes; Solid scintillation detectors;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2007. NSS '07. IEEE

Conference_Location

Honolulu, HI

ISSN

1095-7863

Print_ISBN

978-1-4244-0922-8

Electronic_ISBN

1095-7863

Type

conf

DOI

10.1109/NSSMIC.2007.4436866

Filename

4436866