Title :
MR-Compatible blood sampler for PET
Author :
Breuer, J. ; Grazioso, R. ; Corbeil, J. ; Zhang, N. ; Schmand, M. ; Wienhard, K.
Author_Institution :
Max-Planck-Inst. for Neurological Res., Cologne
fDate :
Oct. 26 2007-Nov. 3 2007
Abstract :
An MR-compatible automatic blood sampler prototype for quantifying radioactivity in blood has been built and tested. The determination of the so-called input function is necessary to investigate the kinetics of the administered radiotracer in PET studies. The counting detector consists of 2 coincident LSO blocks (50times40times 30 mm3) coupled each to a single APD (10 times 10 mm2 active area). Preliminary experimental and numerical results indicate that a specific sensitivity of about 1 cps / (nCi / ml) can be achieved. Tests during bimodal simultaneous MR/PET scans will be carried out in the future with a Siemens 3 T-Trio MR scanner and a brain PET insert.
Keywords :
biomedical MRI; brain; positron emission tomography; 3T-Trio MR scanner; MR-compatible blood sampler; bimodal simultaneous MR-PET scans; brain PET insert; magnetic resonance imaging; radioactivity; radiotracer; Biomedical imaging; Blood; Catheters; Filters; Kinetic theory; Molecular imaging; Photonic crystals; Positron emission tomography; Prototypes; Solid scintillation detectors;
Conference_Titel :
Nuclear Science Symposium Conference Record, 2007. NSS '07. IEEE
Conference_Location :
Honolulu, HI
Print_ISBN :
978-1-4244-0922-8
Electronic_ISBN :
1095-7863
DOI :
10.1109/NSSMIC.2007.4436866