Multiple nuclide imaging in live mouse using semiconductor compton camera for multiple molecular imaging

We have demonstrated the concept of multiple molecular imaging by use of semiconductor Compton cameras. The Compton camera used in this work comprises two double- sided orthogonal-strip germanium detectors, and their excellent energy resolution enables discrimination of the nuclides and accurate determination of the scattering angle especially for sub- MeV to MeV-range gamma rays. Three radioactive tracers of ⁶⁵ZnCl₂, ⁸⁵SrCl₂, and iodinated (¹³¹I) methylnorcholestenol were simultaneously measured in the live-mouse imaging experiment. The images of the three tracers were successfully obtained, which showed the different behavior in the living organism.