Title :
Augmented Active Surface Model for the Recovery of Small Structures in CT
Author :
Bradshaw, Andrew Philip ; Taubman, David S. ; Todd, Michael J. ; Magnussen, John S. ; Halmagyi, G. Michael
Author_Institution :
Dept. of Neurology, R. Prince Alfred Hosp., Camperdown, NSW, Australia
Abstract :
This paper devises an augmented active surface model for the recovery of small structures in a low resolution and high noise setting, where the role of regularization is especially important. The emphasis here is on evaluating performance using real clinical computed tomography (CT) data with comparisons made to an objective ground truth acquired using micro-CT. In this paper, we show that the application of conventional active contour methods to small objects leads to non-optimal results because of the inherent properties of the energy terms and their interactions with one another. We show that the blind use of a gradient magnitude based energy performs poorly at these object scales and that the point spread function (PSF) is a critical factor that needs to be accounted for. We propose a new model that augments the external energy with prior knowledge by incorporating the PSF and the assumption of reasonably constant underlying CT numbers.
Keywords :
computerised tomography; feature extraction; medical image processing; CT numbers; PSF; augmented active surface model; automated image feature extraction; gradient magnitude based energy; high noise setting; low resolution; micro-CT; object scales; objective ground truth; point spread function; real clinical computed tomography data; small structures recovery; Active contours; Computed tomography; Equations; Mathematical model; Smoothing methods; Splines (mathematics); Active contour; B-spline; CT; active surface; ground truth; point spread function; segmentation; semicircular canal; Algorithms; Computer Simulation; Humans; Imaging, Three-Dimensional; Models, Biological; Pattern Recognition, Automated; Radiographic Image Enhancement; Radiographic Image Interpretation, Computer-Assisted; Reproducibility of Results; Sensitivity and Specificity; Tomography, X-Ray Computed; Vestibule, Labyrinth;
Journal_Title :
Image Processing, IEEE Transactions on
DOI :
10.1109/TIP.2013.2273666