Title :
Synaptic Amplification in Motoneurons: Computational and Mechanistic Implications
Author :
Shapiro, Nicholas P. ; Lee, Robert H.
Author_Institution :
Wallace H. Coulter Dept. of Biomed. Eng., Emory Univ., Atlanta, GA
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
Motoneurons are known to possess the latent ability to amplify their inputs in a voltage-dependent manner. Additionally, this synaptic amplification is known to be under neuromodulatory control. This paper presents results from a computer modeling study for one possible mechanism, termed electrotonic compression, which could underlie this behavior
Keywords :
bioelectric potentials; biomembrane transport; finite element analysis; neurophysiology; physiological models; computational implication; computer modeling; electrotonic compression; finite element approximation; ion transporters; mechanistic implication; membrane transport; motoneurons; neuromodulatory control; synaptic amplification; Biomedical engineering; Biomembranes; Cities and towns; Computational modeling; Finite difference methods; Finite element methods; Immune system; Morphology; USA Councils; Voltage control;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.260838
