Title :
Elastic Registration for Auto-fluorescence Image Averaging
Author :
Kubecka, Libor ; Jan, Jiri ; Kolar, Radim ; Jirik, Radovan
Author_Institution :
Dept. of Biomed. Eng., Brno Univ. of Technol.
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
The paper describes restitution of geometrical distortions and improvement of signal-to-noise ratio of auto-fluorescence retinal images, finally aimed at segmentation and area estimation of the lipofuscin spots as one of the features to be included in glaucoma diagnosis. The main problems - geometrical and illumination incompatibility of frames in the image sequence and a non-negligible "shear" distortion in the individual frames - have been solved by the presented registration procedure. The concept and some details of the MI-based regularized registration, together with evaluation of test results form the core of the contribution
Keywords :
diseases; eye; image registration; image segmentation; image sequences; medical image processing; MI-based regularized registration; auto-fluorescence image averaging; auto-fluorescence retinal images; elastic registration; geometrical distortions; glaucoma diagnosis; image segmentation; image sequence; lipofuscin spot area estimation; nonnegligible shear distortion; signal-to-noise ratio improvement; Biomedical measurements; Cities and towns; Design optimization; Image registration; Image sequences; Laser modes; Lighting; Pixel; Retina; Signal to noise ratio;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.260111
