Title :
In-vivo Lung Cancer Imaging in Mice using 360° Free-space Fluorescence Molecular Tomography
Author :
Deliolanis, Nikolaos ; Lasser, Tobias ; Niedre, Mark ; Soubret, Antoine ; Ntziachristos, Vasilis
Author_Institution :
Lab. for Bio-optics & Molecular Imaging, Massachusetts Gen. Hosp., Boston, MA
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
We present the development and performance characteristics of a free-space fluorescence tomography system. The imaging system can capture complete angle projections of photons propagating through tissue in transillumination using a CCD camera. Experimental data on imaging lung cancer are presented. Overall, this imaging approach can offer unprecedented imaging performance in fluorescence molecular tomography of small animals
Keywords :
CCD image sensors; bio-optics; biomedical optical imaging; cancer; fluorescence; lung; molecular biophysics; optical tomography; tumours; CCD camera; angle projections; free-space fluorescence molecular tomography; in-vivo lung cancer imaging; photon propagation; transillumination; Animals; Cancer; Charge coupled devices; Charge-coupled image sensors; Fluorescence; Image reconstruction; Lungs; Mice; Optical imaging; Tomography;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.260683
