Title :
UWB Microwave Breast Cancer Detection: Generalized Models and Performance Prediction
Author :
Chen, Yifan ; Gunawan, Erry ; Kim, Yongmin ; Low, Kay Soon ; Soh, Cheong Boon ; Thi, Lin Lin
Author_Institution :
Biomed. Eng. Res. Centre, Nanyang Technol. Univ.
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
This paper presents a generic framework for the modeling of ultra-wideband (UWB) signal propagation in human breast, which facilitates system-level simulations and provides performance prediction. The clutter associated with the breast tissue heterogeneity is modeled through several key parameters depending on the tissue compositions. Subsequently, important channel properties such as the backscatter energy and the probability density function of time-of-arrival are derived. The modified Hermite polynomials, which fit well into the real pulse shapes, are then used to model the UWB signals. Armed with the channel/signal model preliminaries, three metrics are proposed, namely, the mean clutter response, the clean tumor response, and the worst-case clutter response. The generalized model provides a parsimonious way to study the effects of tissue structures, pulse templates, and array setup on the performance of a specified UWB imaging system. Numerical examples are used to demonstrate the usefulness of the proposed approach
Keywords :
biological organs; biomedical imaging; cancer; microwave imaging; polynomials; probability; tumours; ultra wideband technology; UWB microwave breast cancer detection; UWB microwave imaging; backscatter energy; breast tissue heterogeneity; channel properties; clutter response; generalized models; modified Hermite polynomials; performance prediction; probability density function; pulse templates; statistical clutter modeling; system-level simulations; tissue composition; tissue structures; tumor response; ultra-wideband signal propagation; Backscatter; Breast cancer; Breast tissue; Cancer detection; Humans; Microwave propagation; Polynomials; Predictive models; Probability density function; Ultra wideband technology; UWB microwave imaging; breast cancer detection; pulse shapes; statistical clutter modeling;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.260757