DocumentCode :
471956
Title :
Information Transmission in Hippocampal CA1 Neuron Models in the Presence of Poisson Shot Noise: the Case of Periodic Sub-threshold Spike Trains
Author :
Kawaguchi, Minato ; Mino, Hiroyuki ; Durand, Dominique M.
Author_Institution :
Graduate Sch. of Eng., Kanto Gakuin Univ., Yokohama
fYear :
2006
fDate :
Aug. 30 2006-Sept. 3 2006
Firstpage :
4196
Lastpage :
4199
Abstract :
This article presents an analysis of the information transmission of periodic sub-threshold spike trains in a hippocampal CA1 neuron model in the presence of a homogeneous Poisson shot noise. In the computer simulation, periodic sub-threshold spike trains were presented repeatedly to the midpoint of the main apical branch, while the homogeneous Poisson shot noise was applied to the mid-point of a basal dendrite in the CA1 neuron model consisting of the soma with one sodium, one calcium, and five potassium channels. From spike firing times recorded at the soma, the inter spike intervals were generated and then the probability, p(T), of the inter-spike interval histogram corresponding to the spike interval, r, of the periodic input spike trains was estimated to obtain an index of information transmission. In the present article, it is shown that at a specific amplitude of the homogeneous Poisson shot noise, p(T) was found to be maximized, as well as the possibility to encode the periodic sub-threshold spike trains became greater. It was implied that setting the amplitude of the homogeneous Poisson shot noise to the specific values which maximize the information transmission might contribute to efficiently encoding the periodic sub-threshold spike trains by utilizing the stochastic resonance
Keywords :
Monte Carlo methods; bioelectric potentials; biomembrane transport; brain models; calcium; digital simulation; neurophysiology; potassium; sodium; Ca; Hodgkin-Huxley model; K; Monte Carlo simulation; Na; action potential; basal dendrite; calcium; computer simulation; hippocampal CA1 neuron model; homogeneous Poisson shot noise; information transmission; inter-spike interval histogram; periodic sub-threshold spike trains; potassium channel; sodium; soma; stochastic resonance; synaptic noise; Biomedical engineering; Cities and towns; Computer simulation; Histograms; Nervous system; Neurons; Noise level; Stochastic resonance; Strontium; USA Councils; Action Potential; Hodgkin-Huxley model; Homogeneous Poisson Process; Monte Carlo Simulation; Numerical Method; Shot Noise; Stochastic Resonance; Synaptic Noise;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
ISSN :
1557-170X
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
Type :
conf
DOI :
10.1109/IEMBS.2006.260237
Filename :
4462726
Link To Document :
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