DocumentCode :
472173
Title :
Neural Mass Model of Human Multisensory Integration
Author :
Moran, Rosalyn J. ; Reilly, Richard B.
Author_Institution :
Dept. of Electron. & Electr. Eng., Univ. Coll. Dublin
fYear :
2006
fDate :
Aug. 30 2006-Sept. 3 2006
Firstpage :
5559
Lastpage :
5562
Abstract :
A neural mass model of interacting macro-columns is stimulated to reproduce unisensory, auditory and visually evoked potentials and multisensory (concurrent audiovisual) evoked potentials. These were elicited from patients conducting a reaction response task and recorded from intracranial electrodes placed on the parietal lobe. Important features of this model include inhibitory and excitatory feedback connections to pyramidal cells and extrinsic input to the stellate cell pool, with provision for hierarchical positioning depending on extrinsic connections. Both auditory and visually evoked potentials were best fit using a top-down paradigm. The multisensory response reconstructed from its constituent models was then compared to the actual multisensory EP. Fitting of the multisensory response from constituent models to the actual response required no significant changes to the architecture but did require a decrease in top-down feedback delay. This suggests that multisensory integration, and its related improvement in reaction behavior is not an automatic process but instead controlled by a central executive functioning
Keywords :
auditory evoked potentials; biocontrol; biomedical electrodes; brain; electroencephalography; neurophysiology; physiological models; visual evoked potentials; EEG; auditory potentials; concurrent audiovisual evoked potentials; excitatory feedback connection; hierarchical positioning; human multisensory integration; inhibitory feedback connection; intracranial electrodes; neural mass model; parietal lobe; pyramidal cells; reaction response task; top-down feedback delay; unisensory potentials; visually evoked potentials; Brain modeling; Cities and towns; Electroencephalography; Feedback loop; Humans; Neurons; Physiology; Potential well; Synchronous generators; USA Councils;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
ISSN :
1557-170X
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
Type :
conf
DOI :
10.1109/IEMBS.2006.259588
Filename :
4463065
Link To Document :
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