A Color Visualization Method to the Isochores of DNA Sequences

Isochore is one of the most striking features of the DNA sequences of warm-blooded animals. Isochores affect both coding and non-coding sequences and reflect a fundamental level of genome organization. In this paper, a new method (GCDT) is introduced to display the isochore structures. This method not only can illustrate the isochore structures very well, but also can provide a more detailed description about the GC variation along the genome sequence. GCDT gives an intuitive visual description for the DNA sequences, and matches well with the results of z´ curve.