A Color Visualization Method to the Isochores of DNA Sequences

Author

Wang, Anhui ; Chang, Guiran ; Hu, Minghan

Author_Institution

Sch. of Inf. Sci. & Eng., Northeastern Univ., Shenyang

Volume

5

fYear

2008

fDate

18-20 Oct. 2008

Firstpage

3

Lastpage

7

Abstract

Isochore is one of the most striking features of the DNA sequences of warm-blooded animals. Isochores affect both coding and non-coding sequences and reflect a fundamental level of genome organization. In this paper, a new method (GCDT) is introduced to display the isochore structures. This method not only can illustrate the isochore structures very well, but also can provide a more detailed description about the GC variation along the genome sequence. GCDT gives an intuitive visual description for the DNA sequences, and matches well with the results of z´ curve.

Keywords

DNA; biology computing; cellular biophysics; data visualisation; genetics; molecular biophysics; molecular configurations; DNA sequences; GCDT; coding sequences; color visualization; genome; genome organization; isochores; noncoding sequences; warm-blooded animals; Animal structures; Bioinformatics; Biological cells; DNA computing; Displays; Genomics; Image segmentation; Information science; Sequences; Visualization; DNA; GC-content chromosome; Isochore genome;

fLanguage

English

Publisher

ieee

Conference_Titel

Natural Computation, 2008. ICNC '08. Fourth International Conference on

Conference_Location

Jinan

Print_ISBN

978-0-7695-3304-9

Type

conf

DOI

10.1109/ICNC.2008.654

Filename

4667385