Title :
A Novel Classification Algorithm of Thermostable Proteins by Using Hurst Exponent and SVM Classifier
Author :
Liu, Hsiang-chuan ; Chang, Horngjinh ; Lee, Kuei-jen ; Shieh, Jiunn-i ; Huang, Wen-chun ; Huang, Shin-Ming
Author_Institution :
Dept. of Bioinf., Asia Univ., Taichung
Abstract :
In search of good classification algorithm of thermostable proteins is an important issue. In this paper, a novel classification algorithm of thermostable proteins by using Hurst exponent and SVM classifier is proposed. This method not used before is the first one integrating the physics chemistry properties, fractal property and support vector machine (SVM) classifier. For evaluating the performance of this new algorithm, a real data experiment by using 5 fold and leave-one-out cross-validation accuracy is conducted. Experimental result shows that this new classification algorithm is feasible and useful.
Keywords :
biology computing; pattern classification; proteins; support vector machines; thermal stability; Hurst exponent; SVM classifier; classification algorithm; fractal property; leave-one-out cross-validation accuracy; physics chemistry properties; support vector machine classifier; thermostable proteins; Asia; Bioinformatics; Chemistry; Classification algorithms; Fractals; Physics; Proteins; Psychology; Support vector machine classification; Support vector machines; Hurst Exponent; SVM Classifier; Thermostable Proteins;
Conference_Titel :
Natural Computation, 2008. ICNC '08. Fourth International Conference on
Conference_Location :
Jinan
Print_ISBN :
978-0-7695-3304-9
DOI :
10.1109/ICNC.2008.852