• DocumentCode
    495013
  • Title

    Probabilistic Model for Biological Networks

  • Author

    Du, Cai-Feng ; Xiao, Lan ; Ren, Wei

  • Author_Institution
    Coll. of Math. & Comput. Sci., China Univ. of Pet., Dongying, China
  • Volume
    3
  • fYear
    2009
  • fDate
    21-22 May 2009
  • Firstpage
    266
  • Lastpage
    269
  • Abstract
    Recently there has been considerable interest in studying biological networks such as gene regulatory networks and protein-protein interaction networks. Are biological networks different from other large complex networks? Both large biological and other networks have power law degree distribution, yet the exponents fall into different ranges. This may be because random elimination of the information in the genome is a dominant evolutionary force in shaping biological networks. In this paper, we give a probabilistic model to examine the evolution of biological networks by random elimination processes of node degree as well as the preferential choice mechanisms. For the model, it is proved that there is a stationary power law degree distribution with exponents less than 2, consist with current data on biological networks.
  • Keywords
    biology computing; cellular biophysics; genetics; genomics; molecular biophysics; proteins; random processes; statistical distributions; biological networks; complex networks; gene regulatory networks; genome; power law degree distribution; preferential choice mechanisms; probabilistic model; protein-protein interaction networks; random elimination; Bioinformatics; Biological system modeling; Biology computing; Computer networks; Educational institutions; Fungi; Genomics; Mathematical model; Mathematics; Proteins; biological network; degree distribution; preference; random elimination;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Information and Computing Science, 2009. ICIC '09. Second International Conference on
  • Conference_Location
    Manchester
  • Print_ISBN
    978-0-7695-3634-7
  • Type

    conf

  • DOI
    10.1109/ICIC.2009.273
  • Filename
    5168856