Title :
A Novel Promoter Prediction Method Inspiring by Biological Immune Principles
Author_Institution :
Inst. of Comput., Yantai Univ., Yantai, China
Abstract :
We present an immune recognition algorithm for improving the performance of promoter regions prediction in this paper. We focus on generation of immune detectors by using negative selection operator and clone selection operator. Subsequently, the detectors are evolved. The results of testing on large genomic sequences by comparisons show that our algorithm is efficient with higher sensitivity and specificity in predicting promoter regions.
Keywords :
genetics; pattern recognition; prediction theory; biological immune principles; clone selection operator; genomic sequences; immune detectors; immune recognition algorithm; negative selection operator; promoter prediction method; Bioinformatics; Cloning; Detectors; Evolution (biology); Genetic mutations; Genomics; Immune system; Pathogens; Prediction methods; Sequences; Biological immune; Niching strategy; Promoter prediction; iImmune recognition algorithm;
Conference_Titel :
Intelligent Systems, 2009. GCIS '09. WRI Global Congress on
Conference_Location :
Xiamen
Print_ISBN :
978-0-7695-3571-5
DOI :
10.1109/GCIS.2009.369