Title :
Near-infrared in vivo fluorescence sensor with integrated dielectric emission filter
Author :
O´Sullivan, Thomas D. ; Munro, Elizabeth ; Conca, Christopher ; Parashurama, Natesh ; De La Zerda, Adam ; Gambhir, Sanjiv S. ; Harris, James S. ; Levi, Ofer
Author_Institution :
Solid State & Photonics Lab., Stanford Univ., Stanford, CA, USA
Abstract :
We present a monolithically integrated near-infrared fluorescence sensor incorporating a dielectric emission filter for in vivo applications. We successfully integrated a dielectric emission filter (OD3) onto a low-noise detector and sensed 50 nM fluorescent dye concentration.
Keywords :
biosensors; chemical variables measurement; dielectric devices; dyes; fluorescence; infrared detectors; integrated optics; optical sensors; fluorescent dye concentration; low-noise detector; monolithically integrated dielectric emission filter; near-infrared in vivo fluorescence sensor; optical bio-sensor; Biomedical optical imaging; Detectors; Dielectrics; Fluorescence; In vivo; Optical devices; Optical filters; Optical sensors; Stimulated emission; Vertical cavity surface emitting lasers; (170.3890) Medical optics instrumentation; (230.5160) Photodetectors;
Conference_Titel :
Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-869-8
Electronic_ISBN :
978-1-55752-869-8