Title :
Optical control of neural activity by waveguide delivery in genetically targeted brain tissue
Author :
Zhang, Jiayi ; Laiwalla, Farah ; Kim, Jennifer ; Van Wagenen, Rick ; Song, Yoon-Kyu ; Connors, Barry ; Nurmikko, Arto
Author_Institution :
Dept. of Phys., Brown Univ., Providence, RI, USA
Abstract :
Genetically targeted neurons in brain expressing light sensitive channel Channelrhodopsin can be stimulated optically. We report a novel optical waveguide probe for simultaneous optical stimulation and electrical recording of neurons to modulate neural network behavior.
Keywords :
bio-optics; optical sensors; optical waveguides; electrical recording; genetically targeted brain tissue; genetically targeted neurons; light sensitive channel channelrhodopsin; neural activity; neural network; optical control; optical stimulation; optical waveguide probe; Brain; Neurons; Optical computing; Optical control; Optical fiber networks; Optical modulation; Optical recording; Optical sensors; Optical waveguides; Stimulated emission; 170.3890 Medical optics instrumentation; 170.5380 Physiology;
Conference_Titel :
Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-869-8
Electronic_ISBN :
978-1-55752-869-8
