Title :
High spatial resolution molecular interferometric imaging study of affinity binding
Author :
Zhao, Ming ; Wang, Xuefeng ; Nolte, David
Author_Institution :
Dept. of Phys., Purdue Univ., West Lafayette, IN, USA
Abstract :
We have developed molecular interferometric imaging (MI2) for the fundamental study of affinity binding at surfaces, and present high-resolution data of intra-spot molecular kinetics under mass-transport limitations.
Keywords :
bio-optics; biomedical optical imaging; light interferometry; affinity binding; intraspot molecular kinetics; mass transport; molecular interferometric imaging; surfaces; Biomedical optical imaging; Biosensors; High-resolution imaging; Kinetic theory; Optical distortion; Optical imaging; Optical interferometry; Optical sensors; Proteins; Spatial resolution; (170.1470) Blood/tissue constituent monitoring; (180.3170) Interference microscopy; (260.3160) Interference;
Conference_Titel :
Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-869-8
Electronic_ISBN :
978-1-55752-869-8