Title :
Multimodality optical imaging of atherosclerotic plaques combining optical coherence tomography and fluorescence lifetime imaging
Author :
Jo, Javier A. ; Applegate, Brian E. ; Trivedi, Chintan A. ; Thomas, Patrick ; Jacob, Desmond ; Shelton, Ryan ; Clubb, Fred ; Keller, Brandis
Author_Institution :
Dept. of Biomed. Eng., Texas A&M Univ., College Station, TX, USA
Abstract :
We demonstrate the advantage of combining high-resolution Fourier domain optical coherence tomography (OCT) with wide-field time-gated fluorescence lifetime imaging microscopy (FLIM) for a comprehensive morphological and biochemical characterization of atherosclerotic vulnerable plaques (VP).
Keywords :
biochemistry; biomedical optical imaging; cardiovascular system; fluorescence spectroscopy; optical tomography; atherosclerotic vulnerable plaques; biochemical characterization; comprehensive morphological characterization; high-resolution Fourier domain optical coherence tomography; multimodality optical imaging; wide-field time-gated fluorescence lifetime imaging microscopy; Arteries; Biomedical optical imaging; Fluorescence; High-resolution imaging; Lipidomics; Optical imaging; Optical interferometry; Optical sensors; Spectroscopy; Tomography;
Conference_Titel :
Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-869-8
Electronic_ISBN :
978-1-55752-869-8
