Multimodality optical imaging of atherosclerotic plaques combining optical coherence tomography and fluorescence lifetime imaging

Author

Jo, Javier A. ; Applegate, Brian E. ; Trivedi, Chintan A. ; Thomas, Patrick ; Jacob, Desmond ; Shelton, Ryan ; Clubb, Fred ; Keller, Brandis

Author_Institution

Dept. of Biomed. Eng., Texas A&M Univ., College Station, TX, USA

fYear

2009

fDate

2-4 June 2009

Firstpage

1

Lastpage

2

Abstract

We demonstrate the advantage of combining high-resolution Fourier domain optical coherence tomography (OCT) with wide-field time-gated fluorescence lifetime imaging microscopy (FLIM) for a comprehensive morphological and biochemical characterization of atherosclerotic vulnerable plaques (VP).

Keywords

biochemistry; biomedical optical imaging; cardiovascular system; fluorescence spectroscopy; optical tomography; atherosclerotic vulnerable plaques; biochemical characterization; comprehensive morphological characterization; high-resolution Fourier domain optical coherence tomography; multimodality optical imaging; wide-field time-gated fluorescence lifetime imaging microscopy; Arteries; Biomedical optical imaging; Fluorescence; High-resolution imaging; Lipidomics; Optical imaging; Optical interferometry; Optical sensors; Spectroscopy; Tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on

Conference_Location

Baltimore, MD

Print_ISBN

978-1-55752-869-8

Electronic_ISBN

978-1-55752-869-8

Type

conf

Filename

5226021