Adaptive input estimation of a Hodgkin-Huxley neuron

In this paper, we propose an adaptive observer based on the HH model equations without any linearization method. The nonlinear adaptive observer based on the HH dynamic structure is proposed to estimate the internal states and the input current of a HH neuron. The input current is estimated as a slow-varying parameter using the adaptive parameter update law with a signum function. The MATLAB simulations demonstrate the estimation performance of the proposed adaptive observers.