DocumentCode
50579
Title
Coupled Field Modeling of Ferrofluid Heating in Tumor Tissue
Author
Mateev, Valentin ; Marinova, Iliana ; Saito, Yuya
Author_Institution
Dept. of Electr. Apparatus, Tech. Univ. of Sofia, Sofia, Bulgaria
Volume
49
Issue
5
fYear
2013
fDate
May-13
Firstpage
1793
Lastpage
1796
Abstract
This work examines the method of magnetic fluid hyperthermia for breast cancer therapy. We develop a coupled-field model of ferrofluid transport and heating in tumor tissue. The finite element method (FEM) underpins our forward 3D electromagnetic-fluid dynamics-thermal model. The model uses anatomically precise multilevel geometry of the human breast, with known electrical properties of the tissues, and known speeds of blood and liquor in the breast vessels. We demonstrate the capabilities of the developed model on a real cancer sample acquired by a surgical procedure. The electrical properties of cancer and normal tissues are directly measured for the given sample. The thermal field results are verified by infrared thermograph imaging.
Keywords
bioelectric phenomena; biomedical optical imaging; blood vessels; cancer; finite element analysis; hyperthermia; infrared imaging; magnetic fluids; magnetic particles; physiological models; tumours; 3D electromagnetic-fluid dynamics-thermal model; FEM; anatomically precise human breast multilevel geometry; breast cancer therapy; breast vessel blood speed; breast vessel liquor speed; coupled field modeling; ferrofluid heating; ferrofluid transport; finite element method; infrared thermograph imaging; magnetic fluid hyperthermia; surgical procedure; tissues electrical properties; tumor tissue; Coupled field analysis; electromagnetic field modeling; magnetic liquids; multilevel modeling;
fLanguage
English
Journal_Title
Magnetics, IEEE Transactions on
Publisher
ieee
ISSN
0018-9464
Type
jour
DOI
10.1109/TMAG.2013.2242441
Filename
6514549
Link To Document