• DocumentCode
    50579
  • Title

    Coupled Field Modeling of Ferrofluid Heating in Tumor Tissue

  • Author

    Mateev, Valentin ; Marinova, Iliana ; Saito, Yuya

  • Author_Institution
    Dept. of Electr. Apparatus, Tech. Univ. of Sofia, Sofia, Bulgaria
  • Volume
    49
  • Issue
    5
  • fYear
    2013
  • fDate
    May-13
  • Firstpage
    1793
  • Lastpage
    1796
  • Abstract
    This work examines the method of magnetic fluid hyperthermia for breast cancer therapy. We develop a coupled-field model of ferrofluid transport and heating in tumor tissue. The finite element method (FEM) underpins our forward 3D electromagnetic-fluid dynamics-thermal model. The model uses anatomically precise multilevel geometry of the human breast, with known electrical properties of the tissues, and known speeds of blood and liquor in the breast vessels. We demonstrate the capabilities of the developed model on a real cancer sample acquired by a surgical procedure. The electrical properties of cancer and normal tissues are directly measured for the given sample. The thermal field results are verified by infrared thermograph imaging.
  • Keywords
    bioelectric phenomena; biomedical optical imaging; blood vessels; cancer; finite element analysis; hyperthermia; infrared imaging; magnetic fluids; magnetic particles; physiological models; tumours; 3D electromagnetic-fluid dynamics-thermal model; FEM; anatomically precise human breast multilevel geometry; breast cancer therapy; breast vessel blood speed; breast vessel liquor speed; coupled field modeling; ferrofluid heating; ferrofluid transport; finite element method; infrared thermograph imaging; magnetic fluid hyperthermia; surgical procedure; tissues electrical properties; tumor tissue; Coupled field analysis; electromagnetic field modeling; magnetic liquids; multilevel modeling;
  • fLanguage
    English
  • Journal_Title
    Magnetics, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9464
  • Type

    jour

  • DOI
    10.1109/TMAG.2013.2242441
  • Filename
    6514549