Title :
Hybrid FMT/XCT system validated with ex-vivo fluorescence
Author :
Schulz, RaICH ; Ale, Angelica ; Freyer, Marcus ; Sarantopoulos, Athanasios ; Zientkowska, Marta ; Ntziachristos, Vasilis
Author_Institution :
Intitute for Biological and Medical Imaging, Helmholtz Center Munich and Chair for Biological Imaging, Technical University Munich, Ingolstÿdter LandstraÃ\x9fe 1, 85764 Neuherberg, Germany
Abstract :
Fluorescence tomography can resolve fluorescence biodistribution in vivo with high sensitivity. We use structural information from X-ray CT as priors in the fluorescence reconstruction for improved accuracy, as shown previously [1]. The method was tested on different phantoms and animal models and cross-validated with XCT data, histology and ex vivo fluorescence.
Keywords :
Animals; Biomedical imaging; Biomedical optical imaging; Computed tomography; Fluorescence; Image reconstruction; In vivo; Optical imaging; Optical sensors; X-ray imaging;
Conference_Titel :
Communications and Photonics Conference and Exhibition (ACP), 2009 Asia
Conference_Location :
Shanghai, China
Print_ISBN :
978-1-55752-877-3
Electronic_ISBN :
978-1-55752-877-3
