Title :
Cellular interaction with Si- and iron-based nanoparticles for bio-imaging: A study of biocompatibility
Author :
Rivolta ; Amato, R.D. ; Alexandrescu, R. ; Falconieri, M. ; Morjan, I. ; Chanana, M. ; Bouzas, V. ; Costo, R. ; Fabbr, F. ; Fleacé, C. ; Garcia, M.A. ; Gasco, P. ; Gonzalez, W. ; Morales, M.P. ; Nie, Y. ; Riccio, G. ; Robic, C. ; Sancini, G. ; Vivenza, N.
Author_Institution :
DIMS, Univ. of Milano-Bicocca, Milan, Italy
Abstract :
The overall objective of BONSAI project (FP6, EC) is the development of ultrasensitive bio-imaging techniques based on novel multifunctional nanoparticles (NPs) with tailored optical and magnetic properties for visualizing complex cellular structures (in tissues and organs), receptors, tumour cells and masses. An important aspect to take into consideration involves the cellular responses to the impact of exogenous structures represented by NPs themselves. As a preliminary sign of reaction, we start to investigate the basic cytotoxicity.
Keywords :
biological organs; biological tissues; biomedical imaging; biomedical materials; cellular biophysics; iron compounds; nanobiotechnology; nanoparticles; silicon compounds; tumours; BONSAI project; bio-imaging; bio-imaging techniques; biological organs; cellular interaction; complex cellular structures; cytotoxicity; exogenous structures; iron-based nanoparticles; multifunctional nanoparticles; receptors; tissues; tumour cells; Biomedical optical imaging; Gas lasers; Iron; Magnetic resonance imaging; Nanoparticles; Optical sensors; Production; Silicon; Tumors; Visualization;
Conference_Titel :
Nanotechnology, 2009. IEEE-NANO 2009. 9th IEEE Conference on
Conference_Location :
Genoa
Print_ISBN :
978-1-4244-4832-6
Electronic_ISBN :
1944-9399
