Title :
Carbon nanotubes for targeted drug delivery
Author :
Biale, Chiara ; Mussi, Valentina ; Valbusa, Ugo ; Visentin, Sonja ; Viscardi, Guido ; Barbero, Nadia ; Pedemonte, Nicoletta ; Galietta, Luis
Author_Institution :
Italian Inst. of Technol. (IIT), Genova, Italy
Abstract :
The use of carbon nanotubes (CNTs) as vectors for targeted drug delivery was recently considered, thanks to their ability to permeate the cellular membrane which, instead, results highly refractory to transfer with other vectors (viral and not viral). Our project is devoted to define and characterize a CNTs based nanocompound for gene-moduling, with the final aim of complementing defective functions in cystic fibrosis transmembrane conductance regulator (CFTR) gene.
Keywords :
bioelectric phenomena; biological tissues; biomedical materials; biomembranes; carbon nanotubes; cellular biophysics; diseases; drugs; genetics; nanobiotechnology; C; CFTR; carbon nanotubes; cellular membrane; cystic fibrosis transmembrane conductance regulator gene; gene-moduling; permeation; targeted drug delivery; viral vectors; Carbon nanotubes; Nanotechnology Council; Targeted drug delivery; Cystic Fibrosis; Single Wall Carbon Nanotube; drug delivery;
Conference_Titel :
Nanotechnology, 2009. IEEE-NANO 2009. 9th IEEE Conference on
Conference_Location :
Genoa
Print_ISBN :
978-1-4244-4832-6
Electronic_ISBN :
1944-9399
