DocumentCode
519023
Title
A novel multi-task support vector sample learning technique to predict classification of cancer
Author
Chen, Austin H. ; Tsau, Yin-Wu ; Wang, Yu-Chieh
Author_Institution
Dept. of Med. Inf., Tzu-Chi Univ., Hualien, Taiwan
fYear
2010
fDate
11-13 May 2010
Firstpage
196
Lastpage
200
Abstract
We have implemented a systematic method that can improve cancer classification. By extracting significant samples (which we refer to as support vector samples because they are located only on support vectors), we can let the back propagation neural networking (BPNN) to learn more tasks. We call this approach the multi-task support vector sample learning (MTSVSL) technique. We demonstrate experimentally that the genes selected by our MTSVSL method yield super classification performance by applying to leukemia and prostate cancer gene expression datasets. Our proposed MTSVSL method is a novel approach that is expedient and can produce very good performance in cancer diagnosis and clinical outcome prediction. Our method has been successfully applied to cancer type-based classifications on microarray gene expression. MTSVSL can improve the accuracy of traditional BPNN architecture.
Keywords
backpropagation; cancer; medical computing; molecular biophysics; neural nets; pattern classification; support vector machines; backpropagation neural network; cancer classification; leukemia; microarray gene expression; multitask support vector sample learning; prostate cancer; sample extraction; Accuracy; Bioinformatics; Biomedical informatics; DNA; Gene expression; Genomics; Neural networks; Prostate cancer; Support vector machine classification; Support vector machines; back propagation neural networking; cancer classification; gene expression profiling; multi task learning; support vectors;
fLanguage
English
Publisher
ieee
Conference_Titel
New Trends in Information Science and Service Science (NISS), 2010 4th International Conference on
Conference_Location
Gyeongju
Print_ISBN
978-1-4244-6982-6
Electronic_ISBN
978-89-88678-17-6
Type
conf
Filename
5488621
Link To Document