Multichannel bipotentiostat system for cellular monitoring platforms

Author

Vergani, Marco ; Carminati, Marco ; Ferrari, Giorgio ; Adamovski, Miriam

Author_Institution

Dipt. di Elettron. e Inf., Politec. di Milano, Milan, Italy

fYear

2010

fDate

18-21 July 2010

Firstpage

1

Lastpage

4

Abstract

A versatile 4-channel bipotentiostat system for biochemical sensing is presented. A 1pA current resolution and 8 kHz bandwidth are suited for amperometric detection of neurotransmitters released by cells, monitored in a smart microfluidic culture chamber. Multiple electrochemical measurements can be carried out on arrays of microelectrodes. Key design issues are here discussed along with the results of extensive electrochemical experiments (cyclic voltammetry, chronoamperometry, redox recycling and potentiometry).

Keywords

amperometric sensors; biochemistry; bioelectric potentials; biological techniques; cellular biophysics; microelectrodes; molecular biophysics; neurophysiology; oxidation; reduction (chemical); voltammetry (chemical analysis); 4-channel bipotentiostat system; amperometric detection; bandwidth 8 kHz; biochemical sensing; cellular monitoring; chronoamperometry; current 1 pA; cyclic voltammetry; microelectrode arrays; multichannel bipotentiostat system; neurotransmitters; potentiometry; redox recycling; smart microfluidic culture chamber; Bandwidth; Capacitance; Current measurement; Electric potential; Electrodes; Instruments; Noise; cell monitoring; electrochemical measurements; neurotransmitter detection;

fLanguage

English

Publisher

ieee

Conference_Titel

Ph.D. Research in Microelectronics and Electronics (PRIME), 2010 Conference on

Conference_Location

Berlin

Print_ISBN

978-1-4244-7905-4

Type

conf

Filename

5587125