Correlations between speed of sound and microstructure in swine cancellous bone during decalcification

Author

Shao, Xiaoning ; Niu, Haijun ; Fan, Yubo ; Li, Deyu ; Pu, Fang ; Pei, Baoqing ; Sun, Lianwen

Author_Institution

Sch. of Biol. Sci. & Med. Eng., Beihang Univ., Beijing, China

Volume

2

fYear

2010

fDate

16-18 Oct. 2010

Firstpage

833

Lastpage

837

Abstract

The aim of this in vitro study is to explore the correlations between quantitative ultrasound (QUS) parameters and micro-structure parameters of cancellous bone. Cube of swine cancellous bone were resort to progressively decalcification and subjected to QUS and micro computed tomography. Ethylene Diamine Tetraacetic Acid (EDTA) decalcification was used to remove calcium. SOS, an important QUS parameter, has a downtrend as calcium run off. At the same time, both BV/TV and Tb.Th have a downtrend; meanwhile, BS/BV and Tb.Pf have an uptrend during the process of decalcification. SOS shows a great correlation with Micro-Structure parameters which indicate that quantitative ultrasound has the potential to reflect bone microstructure.

Keywords

biomedical ultrasonics; bone; computerised tomography; ethylene diamine tetraacetic acid decalcification; microcomputed tomography; microstructure; quantitative ultrasound parameters; sound speed; swine cancellous bone; Acoustics; Bones; Cancellous bone; Correlation; TV; Ultrasonic imaging; Ultrasonic variables measurement; cancellous bone; decalcification; micro-structure; osteoporosis; speed of sound;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Engineering and Informatics (BMEI), 2010 3rd International Conference on

Conference_Location

Yantai

Print_ISBN

978-1-4244-6495-1

Type

conf

DOI

10.1109/BMEI.2010.5639923

Filename

5639923