Title :
GRACE: A Visual Comparison Framework for Integrated Spatial and Non-Spatial Geriatric Data
Author :
Maries, Adrian ; Mays, Nathan ; Hunt, Megan Olson ; Wong, Kim F. ; Layton, William ; Boudreau, Richard ; Rosano, Caterina ; Marai, G. Elisabeta
Author_Institution :
Dept. of Comput. Sci., Univ. of Pittsburgh, Pittsburgh, PA, USA
Abstract :
We present the design of a novel framework for the visual integration, comparison, and exploration of correlations in spatial and non-spatial geriatric research data. These data are in general high-dimensional and span both the spatial, volumetric domain - through magnetic resonance imaging volumes - and the non-spatial domain, through variables such as age, gender, or walking speed. The visual analysis framework blends medical imaging, mathematical analysis and interactive visualization techniques, and includes the adaptation of Sparse Partial Least Squares and iterated Tikhonov Regularization algorithms to quantify potential neurologymobility connections. A linked-view design geared specifically at interactive visual comparison integrates spatial and abstract visual representations to enable the users to effectively generate and refine hypotheses in a large, multidimensional, and fragmented space. In addition to the domain analysis and design description, we demonstrate the usefulness of this approach on two case studies. Last, we report the lessons learned through the iterative design and evaluation of our approach, in particular those relevant to the design of comparative visualization of spatial and non-spatial data.
Keywords :
biomedical MRI; data visualisation; geriatrics; iterative methods; least squares approximations; medical image processing; neurophysiology; GRACE; abstract visual representation; comparative visualization; design description; domain analysis; integrated spatial data; interactive visual comparison; interactive visualization techniques; iterated Tikhonov regularization algorithms; iterative design; magnetic resonance imaging volumes; mathematical analysis; medical imaging; neurologymobility connections; nonspatial data; nonspatial domain; nonspatial geriatric data; nonspatial geriatric research data; sparse partial least squares; spatial representation; visual analysis framework; visual comparison framework; visual integration; Algorithm design and analysis; Biomedical imaging; Brain modeling; Data visualization; Geriatrics; Rendering (computer graphics); Algorithm design and analysis; Biomedical imaging; Brain modeling; Data visualization; Design studies; Geriatrics; Rendering (computer graphics); applications of visualization; high-dimensional data; integrating spatial and non-spatial datavisualization; methodology design; task and requirements analysis; visual comparison; Aged; Aged, 80 and over; Algorithms; Computer Graphics; Decision Support Systems, Clinical; Diagnosis, Computer-Assisted; Female; Geriatric Assessment; Humans; Imaging, Three-Dimensional; Male; Reproducibility of Results; Sensitivity and Specificity; Software; Systems Integration; User-Computer Interface;
Journal_Title :
Visualization and Computer Graphics, IEEE Transactions on
DOI :
10.1109/TVCG.2013.161