• DocumentCode
    544256
  • Title

    Active analog approach to Histamine HI receptor antagonists

  • Author

    Ritter, A. ; Gerula, Christine M. ; Yadav, J.

  • Author_Institution
    Dept. of Physiol., Univ. of Med. & Dentistry of NJ, Newark, NJ, USA
  • Volume
    1
  • fYear
    1992
  • fDate
    Oct. 29 1992-Nov. 1 1992
  • Firstpage
    208
  • Lastpage
    210
  • Abstract
    Molecular modeling studies have been carried out to compare static, electronic and electrostatic properties of some Histamine H1 receptor antagonists using SYBYL package. The present work does suggest a correlation between structure function relationships of these molecules.
  • Keywords
    biochemistry; bioelectric phenomena; biology computing; drugs; electrostatics; molecular biophysics; physiological models; proteins; SYBYL package; active analog approach; electronic properties; electrostatic properties; histamine H1 receptor antagonists; molecular modeling; static properties; structure function relationships; Computational modeling; Electrostatics; Periodic structures;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 1992 14th Annual International Conference of the IEEE
  • Conference_Location
    Paris
  • Print_ISBN
    0-7803-0785-2
  • Electronic_ISBN
    0-7803-0816-6
  • Type

    conf

  • DOI
    10.1109/IEMBS.1992.5760929
  • Filename
    5760929
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=544256