Low power density V.S. high power density photocoagulation of ventricular myocardium for cardiac arrhythmias. Observations supporting non-linear tissue optics

Author

Svenson, Robert H. ; Splinter, Robert ; Littmann, Laszlo ; Chuang, Chi Hui ; Tuntelder, Jan R. ; Thompson, Michelle ; Dezern, Kathy R. ; Tatsis, George P. ; Brucker, Greg ; Raja, M. Yasin Akhtar

Author_Institution

Laser & Appl. Technol. Lab., Carolinas Heart Inst. & Carolinas Med. Center, Charlotte, NC, USA

Volume

1

fYear

1992

fDate

Oct. 29 1992-Nov. 1 1992

Firstpage

318

Lastpage

319

Abstract

Nd:YAG laser photocoagulation of canine myocardium using low power density (LPD) laser irradiation was compared with high power density (HPD) irradiation. LFD irradiation (102 W/cm²) produced lesions of mean maximum depth at 320 joules of 4.8 mm with width exceeding depth. HPD irradiation (16,000-24,000 W/cm²) achieved depth of 9.5 to 11.5 mm at 300 joules or less. LPD lesions are consistent with light dosimetry calculations from the known optical parameters of canine myocardium. However, these calculated dosimetries cannot account for lesions produced by HPD irradiation. This finding suggests the possibility of non-linear optical properties in biologic tissue.

Keywords

bio-optics; cardiovascular system; coagulation; diseases; dosimetry; laser applications in medicine; muscle; radiation therapy; Nd:YAG laser photocoagulation; YAG:Nd; cardiac arrhythmias; high power density laser irradiation; lesion; light dosimetry calculation; low power density laser irradiation; nonlinear optical property; nonlinear tissue optics; ventricular myocardium; Heart; Integrated optics; Myocardium; Power lasers;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1992 14th Annual International Conference of the IEEE

Conference_Location

Paris

Print_ISBN

0-7803-0785-2

Electronic_ISBN

0-7803-0816-6

Type

conf

DOI

10.1109/IEMBS.1992.5760983

Filename

5760983