Title :
Micromechanical behavior of neutrophils via micropore filtration approach
Author :
Nikita, K.S. ; Uzunoglu, N.K. ; Koutsouris, D.
Author_Institution :
Biomedicai Engineering Unit, Department of Electrical and Computer Engineering, National Technical University of Athens, Athens 10682. Greece
fDate :
Oct. 29 1992-Nov. 1 1992
Abstract :
Neutrophils Theological behavior has been studied by using a new micropore filtration system system, the Cell Transit Analyzer (CTA) Micromechanical parameters of neutrophils have been estimated by measuring the change in electrical conductance produced across the mieropores. By using the CTA, both the mean transit time for the entire cell population and the frequency histogram of transit times for more than 100 cells within 4–5 minutes are provided Experiments have been performed with normal and artificially alterred microphils. Dependence of neutrophils transit times upon pH and osmolality has been investigated.
Keywords :
Biomedical measurements; Cells (biology); Electric variables measurement; Filtering theory; Mechanical factors; Rheology; White blood cells;
Conference_Titel :
Engineering in Medicine and Biology Society, 1992 14th Annual International Conference of the IEEE
Conference_Location :
Paris, France
Print_ISBN :
0-7803-0785-2
Electronic_ISBN :
0-7803-0816-6
DOI :
10.1109/IEMBS.1992.5761163
