Title :
An expert system model for detection of lymphocyte subsets
Author :
Rao, Gururajan R. ; Suresh, B.A. ; Scolpino, Anthony S. ; Denny, Thomas N.
Author_Institution :
Center for Lab. Investig., UMD, Newark, NJ, USA
fDate :
Oct. 29 1992-Nov. 1 1992
Abstract :
Flow cytometric analysis permits us to use known combinations of monoclonal antibodies in immunophenotyping the path of lymphocytic leukemia, non-hodgkin lymphomas and HIV associated diseases. Our expert system model utilizes the values obtained from Flow Cytometric analysis in order to characterize cell maturation stages and thereby diagnose the disease state using known facts. KEE (Knowledge Engineering Environment) is used to implement this expert system as a diagnostic and research tool.
Keywords :
blood; cancer; cellular biophysics; diagnostic expert systems; knowledge engineering; medical diagnostic computing; HIV; KEE; cell maturation stages; expert system model; flow cytometry; immunophenotyping; knowledge engineering environment; lymphocytic leukemia; monoclonal antibodies; nonHodgkin lymphomas; Cognition;
Conference_Titel :
Engineering in Medicine and Biology Society, 1992 14th Annual International Conference of the IEEE
Conference_Location :
Paris
Print_ISBN :
0-7803-0785-2
Electronic_ISBN :
0-7803-0816-6
DOI :
10.1109/IEMBS.1992.5761276
