Title :
The influence of the ceramic phase on the structure of resorbable biocomposites based on collagen
Author :
Antoniac, I. ; Vrânceanu, M.D. ; Antoniac, A. ; Albu, M.G.
Author_Institution :
Univ. Politeh. of Bucharest, Bucharest, Romania
Abstract :
Collagen: hidroxyapatite and collagen: betatricalcium compositions were prepared by lyophylization and spongious composites for regeneration of bone defects were obtained. The spongious composites were characterized by Fourier transform infra-red (FT-IR) spectroscopy, scanning electron microscopy (SEM) and enzymatic degradation by collagenase. The results showed spongious composites with interconected pores of 20-150 μm with embedded particles of mineral phase. Their biodegradation is less for composite with 25:75 (Coll/HAp or Coll/ β-TCP) as results of FT-IR and collagenase degradation showed. Due to their properties, the obtained composites could be potential biomaterials for bone tissue engineering.
Keywords :
Fourier transform spectra; bioceramics; biochemistry; biodegradable materials; bone; calcium compounds; composite materials; enzymes; infrared spectra; molecular biophysics; scanning electron microscopy; tissue engineering; Ca10(PO4)6(OH)2; FTIR; Fourier transform infrared spectroscopy; SEM; betatricalcium compositions; biodegradation; biomaterials; bone defect generation; bone tissue engineering; ceramic phase; collagen; collagenase; embedded particles; enzymatic degradation; hidroxyapatite; lyophylization; resorbable biocomposites; scanning electron microscopy; size 20 mum to 150 mum; spongious composites; Bones; Ceramics; Chemicals; Degradation; Minerals; Scanning electron microscopy; betatricalcium phosphate; collagen; composites; hydroxyapatite;
Conference_Titel :
E-Health and Bioengineering Conference (EHB), 2011
Conference_Location :
Iasi
Print_ISBN :
978-1-4577-0292-1
