Influence of magnesium doping on synthesized hydroxyapatite using the wet precipitation method

The influence of magnesium doping on hydroxypatite represents an important research topic because of the enhancements it brings without affecting the biocompatibility. In the last decade many substances have been used for doping hydroxypatite like F, Mg, CO₃, Mn, Zn, Bi, Na but each brought some disadvantages like worse mechanical properties or citotoxicity. The present study investigates the influence of Mg quantity on the stoichiometry of the final ceramic powder compared to pure HA. The ceramic powders were synthesized through the wet precipitation method using a bioreactor with double walls through which a thermo-conductive fluid circulates with the help of a thermostat. The parameters for both HA and Mg-HA synthesis were identical, reactants, temperature of 50°C, stirring speed of 220 rpm, duration of 20 h and pH 11. The Mg-HA powder was obtained using different quantities of magnesium, respectively 1 wt% and 5 wt%, for comparison. After the maturation the precipitates were dried, calcined and prepared for XRD analysis to check the chemical composition and the stoichiometry. The XRD showed the presence of MgO in both cases of 1 wt% respectively 5 wt%. Also the Mg-HA samples and the pure HA achieved the Ca/P of 1.67 same as the pure HA.