Cardiovascular model for development and test of automated hemodynamic regulation with medication

After cardiac surgery patients are transferred to the intensive care unit for recovery. Physicians assess the patient´s hemodynamic state every now and then and apply medication, if needed. This time consuming task may be done by an automated hemodynamic regulation, allowing a more continuous regulation reducing the time of recovery and enabling physicians to attend more critical tasks. To develop such a controller, extensive tests and evaluation of its performance in different situations is needed. In this paper we describe a simulation model that allows extensive evaluation of the automated regulation. This model is able to simulate the human cardiovascular system with different common disorders. Also adequate reactions to four types of drugs were implemented. The simulation of both the disorders and the reactions to drug infusions were configured to fit physiological data collected from previous animal experiments.