Title :
Cardiovascular regulation in different sleep stages in the obstructive sleep apnea syndrome
Author :
Kraemer, Jan F. ; Gapelyuk, Andrej ; Riedl, Maik ; Suhrbier, Alexander ; Bretthauer, Georg ; Malberg, Hagen ; Penzel, Thomas ; Kurths, Jürgen ; Wessel, Niels
Author_Institution :
Dept. of Phys., Humboldt-Univ. zu Berlin, Berlin, Germany
Abstract :
In order to show the value of the analysis of heart rate variability (HRV), blood pressure variability (BPV) and baroreflex sensitivity (BRS) for the study of sleep disorders we consider 38 subjects, 18 of which are normotensive (NT) and 10 hypertensive (HT) patients suffering from obstructive sleep apnea syndrome (OSAS), the rest being controls. To detect differences in cardiovascular regulation between the different sleep stages and these age and sex matched groups, linear and nonlinear parameters are used. The therapeutic effect of continuous positive airway pressure (CPAP) therapy is investigated by comparing an initial diagnostic measurement with a follow-up after three month of therapy.
Keywords :
blood; cardiovascular system; diseases; medical disorders; patient treatment; sensitivity; sleep; age matched groups; baroreflex sensitivity; blood pressure variability; cardiovascular regulation; continuous positive airway pressure theraphy; diagnostic measurement; heart rate variability; hypertensive patients; normotensive patients; obstructive sleep apnea syndrome; sex matched groups; sleep disorders; therapeutic effect; Blood pressure; Frequency domain analysis; Heart rate variability; Physics; Sleep apnea;
Conference_Titel :
Computing in Cardiology, 2011
Conference_Location :
Hangzhou
Print_ISBN :
978-1-4577-0612-7
