Fragmentation in Body Surface Potential Mapping recordings from patients with Brugada syndrome

Author

Fonseca-Guzmán, A. ; Climent, A.M. ; Millet, J. ; Berné, P. ; Brugada, J. ; Ramos, R. ; Brugada, R. ; Guillem, M.S.

Author_Institution

BioITACA, Univ. Politec. de Valencia, Valencia, Spain

fYear

2011

fDate

18-21 Sept. 2011

Firstpage

637

Lastpage

640

Abstract

Brugada syndrome (BrS) causes sudden death in patients with structurally normal hearts. Manifestation of BrS in the ECG is dynamic and most patients do not show unequivocal signs of the syndrome during ECG screening. Fragmentation of QRS complexes in BrS patients has been linked to a worse prognosis and higher risk. In this study we aim to determine the spatial location of fragmented ECG signals in BrS and controls in order to elucidate its potential role in the diagnosis of BrS and the identification of patients with a higher risk. We obtained 67-lead Body Surface Potential Mapping recordings of 38 BrS, 28 Right Bundle Branch Block (RBBB) patients and 16 controls. Fragmentation of QRS complexes appeared in the anterior torso of symptomatic BrS patients with a higher incidence than in asymptomatic individuals. P waves of symptomatic BrS patients were more fragmented than in other groups.

Keywords

bioelectric potentials; diseases; electrocardiography; patient diagnosis; surface potential; Brugada syndrome Patients; ECG; QRS complexes; anterior torso; asymptomatic individuals; body surface potential mapping recordings; fragmentation; right bundle branch block patients; spatial location; structurally normal hearts; Electric potential; Electrocardiography; Heart; IIR filters; Indexes; Low pass filters; Torso;

fLanguage

English

Publisher

ieee

Conference_Titel

Computing in Cardiology, 2011

Conference_Location

Hangzhou

ISSN

0276-6547

Print_ISBN

978-1-4577-0612-7

Type

conf

Filename

6164646