Title :
Experimental Observations of Animal Neck Injuries under Whiplash Simulations
Author :
Chen, Haibin ; Tang, He ; Cheng, Xuemei ; Li-Ying Zhang ; Wang, Zheng-guo
Author_Institution :
State Key Lab. of Trauma, Burns, & Combine Injury, Third Mil. Med. Univ., Chongqing, China
fDate :
July 31 2012-Aug. 2 2012
Abstract :
Up to now, the mechanism of neck whiplash injuries is not completely understood. One of the reasons is that it is difficult to establish an animal model subjected to whiplash-type injuries (especially for the animal model of cervical spinal cord injury). For this reason, a new experimental setup was designed to simulate the whiplash extension exposure in the neck of dogs. Based on the related detections (i. e., the behavior assessment, light microscopy, neuropotential measurement, gross observation and MRI auxiliary examination), a consistent finding was obtained as follows: the behavior function and nerve conduction function of neck spinal cord were impaired and the impairment extent was positively associated with the peak value of head posterior traction acceleration; namely, the greater the posterior acceleration peak was, the severer the related function impairment of neck spinal cord would be.
Keywords :
biomedical MRI; injuries; neurophysiology; optical microscopy; MRI auxiliary examination; animal neck injuries; cervical spinal cord injury; head posterior traction acceleration; light microscopy; neck spinal cord; neck whiplash injuries; nerve conduction function; neuropotential measurement; posterior acceleration peak; whiplash extension exposure; whiplash simulation; Acceleration; Animals; Head; Injuries; Neck; Neurons; Spinal cord; Animal model; Combined behavior score; HE staining; Holmes argyrophil staining; Neck injuries; Nissl´s staining; Spinal cord; Whiplash simulation;
Conference_Titel :
Digital Manufacturing and Automation (ICDMA), 2012 Third International Conference on
Conference_Location :
GuiLin
Print_ISBN :
978-1-4673-2217-1
DOI :
10.1109/ICDMA.2012.95