Evaluation of pulse wave velocity using 4D CT Cardiogram

The total arterial compliance (TAC) is defined as the sum of systemic arterial compliance which could be calculated at the root of aorta. It is an index to assess the status of arterial stiffness. Pulse wave velocity (PWV) is becoming a clinical index to assess the level of arterial stiffness. This abstract will be discussed the methodology of evaluation of PWV that will be correlating with TAC using 4D CT Cardiogram. Fifteen subjects´ 4D CT cardiograms were using in this study. The aortic volume calculated at the aortic root from 4D cardiac images were ranging from 68.9 ml to 97 ml. The data was checked against the cardio outputs from the Left Ventricular (LV) images with excellent correlation (R = 0.970, P <;0.01). The PWV was calculated from difference of distance that divided to the time difference (Δd/Δs). The PWVs were ranging from 7.8 to 15.6 m/s. The data was positively correlated to the total compliance calculated at the aortic root (R = 0.672, p <; 0.01). And, the PWV was negatively correlated to the distention of aorta (R=-0.855, P<;0.01). The derived methodology to calculate PWV from 4D CT cardiac images could be used as an index in evaluation of arterial stiffness.