Title :
Novel approach to power spectrum estimation of DNA sequence by Prony´s method
Author :
Roy, Matthieu ; Barman, S.
Author_Institution :
Calcutta Tech. Sch., Kolkata, India
Abstract :
Digital Spectral Analysis of DNA sequence using AR Models have long been proved to be superior to classical Fourier Transform techniques. Here authors have applied a special case of all-pole model using Prony´s method to DNA sequence from various Chromosomes for Power Spectral Density (PSD) estimation in order to identify protein-coding regions. A quaternary mapping method comprising real and imaginary values towards nucleotide bases has been employed. The simulation results obtained by Prony´s model clearly show the demarcation between coding and non-coding regions of DNA sequence.
Keywords :
DNA; Fourier transforms; biology computing; cellular biophysics; molecular biophysics; molecular configurations; proteins; sequential estimation; spectral analysis; transform coding; AR models; DNA sequence; Prony method; all-pole model; chromosomes; classical Fourier transform; digital spectral analysis; power spectral density estimation; protein-coding regions; quaternary mapping method; superior Fourier transform; Bioinformatics; Computational modeling; DNA; Encoding; Estimation; Mathematical model; Spectral analysis; Auto-regressive; Classical; Codon; Parametric; Power Spectral Density;
Conference_Titel :
Communications, Devices and Intelligent Systems (CODIS), 2012 International Conference on
Conference_Location :
Kolkata
Print_ISBN :
978-1-4673-4699-3
DOI :
10.1109/CODIS.2012.6422201
