DocumentCode :
594178
Title :
Theoretical investigation of near-infrared light path in multi-layer brain models for three DOT systems
Author :
Xiaowei Zhou ; Ling Chen ; Chun-Yu Tse ; Penney, T.B. ; Nanguang Chen
Author_Institution :
Dept. of Bioeng., Nat. Univ. of Singapore, Singapore, Singapore
fYear :
2012
fDate :
13-16 Dec. 2012
Firstpage :
1
Lastpage :
5
Abstract :
The optical path of near-infrared light propagation in multi-layer brain models was investigated by theoretical and computational analysis for three DOT systems. The brain models are comprised a three-layer slab or three-layer semi-sphere intersected by a same size three-layer slab. In each model, the light penetration depths and the shapes of light paths for different source and detector pairs were analyzed with a numerical diffusion forward model based on the finite element method. The simulation results revealed that the light path was affected by source and detector distance, and varied in the different brain models. Specifically, the effective penetration depths were different for the different DOT systems and deeper penetration depth was observed using a fast time-domain DOT system.
Keywords :
biomedical optical imaging; brain models; finite element analysis; infrared spectroscopy; light propagation; multilayers; optical tomography; detector distance; diffuse optical tomography; fast time-domain DOT system; finite element method; light path shapes; light penetration depths; multilayer brain model; near-infrared light path propagation; near-infrared spectroscopy; numerical diffusion forward model; numerical simulation; source distance; three-layer semisphere; three-layer slab; Detectors; Head; Mathematical model; Optical sensors; Sensitivity; Slabs; US Department of Transportation; DOT systems; Near infrared light; penetration depth; tissue spatial sensitivity;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Photonics Global Conference (PGC), 2012
Conference_Location :
Singapore
Print_ISBN :
978-1-4673-2513-4
Type :
conf
DOI :
10.1109/PGC.2012.6458116
Filename :
6458116
Link To Document :
بازگشت