The making and evaluating of animal models of obsessive-compulsive disorder

Objective: We combine the reviews about methods of making obsessive-compulsive disorder animal models in recent years, with practical needs of basic researches together, to effect evaluation as to these kind of models, and eventually, to improve basic researches. Method: Literature searches are applied to obtain our Objective. Result: At present the animal models of obsessive-compulsive disorder can be mainly divided into four categories: pharmacological models, behavioral models, surgical models and genetic models. Conclusion: Different methods of modeling lead to different features of the models. Models should be made according to research need.