Title :
Prediction of Tubulin Resonant Frequencies Using the Resonant Recognition Model (RRM)
Author :
Cosic, Irena ; Lazar, Katarina ; Cosic, Drasko
Author_Institution :
RMIT Univ., Melbourne, VIC, Australia
Abstract :
Tubulin proteins were analyzed using the Resonant Recognition Model to predict possible electromagnetic resonances in tubulin and microtubules. We propose that these electromagnetic resonances are caused by charge transfer through the protein molecule. The frequencies of these electromagnetic resonances depend on charge velocity. Using different velocities of charge transfer, we predicted resonant frequencies in different frequency ranges from KHz to THz. These resonant frequencies could be relevant for taxol binding as well as a possible role of microtubules as a macromolecular computer.
Keywords :
charge exchange; molecular biophysics; physiological models; proteins; charge transfer velocities; electromagnetic resonance prediction; macromolecular computer; microtubules; protein molecule; resonant recognition model; taxol binding; tubulin resonant frequency; Amino acids; Charge transfer; Phonons; Proteins; Resonant frequency; Molecular modeling; protein resonances; resonant recognition model; signal processing; tubulin;
Journal_Title :
NanoBioscience, IEEE Transactions on
DOI :
10.1109/TNB.2014.2365851