Title :
Mri of spio-labeled mesenchymal stem cells in an animal model of acute renal failure at a clinical 3T system
Author :
Ittrich, H. ; Lange, C. ; Toegel, F. ; Zander, A.R. ; Westenfelder, C. ; Adam, Grain ; Nolte-Ernsting, C.
Author_Institution :
Dept. of Diagnostic & Interventional Radiol., Univ. Med. Center Hamburg-Eppendorf, Hamburg, Germany
Abstract :
Optimized methods in MRI allow for qualitative and quantitative in-vivo cell-tracking and monitoring of organ distribution of SPIO-labeled MSC in clinical acute renal failure (ARF) in rate at a clinical 3T MR system. The study demonstrates the potential of in-vivo MRI for qualitative tracking and quantification of SPIO-labeled stem cells in future therapeutic treatment protocols.
Keywords :
biomedical MRI; cellular biophysics; diseases; iron compounds; kidney; Fe2O3; SPIO-labeled MSC; SPIO-labeled mesenchymal stem cells; animal model; clinical MR system; clinical acute renal failure; in-vivo MRI; in-vivo cell-tracking; magnetic flux density 3 T; organ distribution; superparamagnetic iron oxide; Animals; Bones; Educational institutions; Kidney; Magnetic resonance imaging; Signal to noise ratio; Stem cells;
Conference_Titel :
Magnetic Particle Imaging (IWMPI), 2013 International Workshop on
Conference_Location :
Berkeley, CA
Print_ISBN :
978-1-4673-5520-9
Electronic_ISBN :
978-1-4673-5521-6
DOI :
10.1109/IWMPI.2013.6528362
