Title :
Data integration model for cancer subtype identification using Kernel Dimensionality Reduction-Support Vector Machine (KDR-SVM)
Author :
Wasito, Ito ; Istiqlal, A.N. ; Budi, Indra
Author_Institution :
Fac. of Comput. Sci., Univ. Indonesia, Depok, Indonesia
Abstract :
In this paper, an integration model of cancer patients data types such as microarray DNA and clinical data will be experimentally explored. The data of integration will be used for cancer subtype identification using kernel based classification methods which is the extension of Support Vector Machine (SVM) approach with Kernel Dimensionality Reduction (KDR). KDR-SVM method will be implemented in Lymphoma cancer database and the relevant clinical information. Data type representation will be modeled in an appropriate kernel matrix. The results of the experiment show that the KDR-10 dimensions and data integration can improve the accuracy of the identification of subtype cancer.
Keywords :
cancer; data integration; lab-on-a-chip; matrix algebra; medical information systems; support vector machines; KDR-10 dimensions; KDR-SVM method; Lymphoma cancer database; cancer patient data type integration model; cancer subtype identification; clinical data; data integration model; data type representation; kernel based classification methods; kernel dimensionality reduction-support vector machine; kernel matrix; microarray DNA; Clinical Data; Data Integration; Kernel Dimensionality Reduction; Kernel Matrix; Microarray data; Support Vector Machine;
Conference_Titel :
Computing and Convergence Technology (ICCCT), 2012 7th International Conference on
Conference_Location :
Seoul
Print_ISBN :
978-1-4673-0894-6