MicroRNAs: Unspecific Inhibitory Regulation in Immunologic Control and in Mitochondrial Respiration

The microRNAs are responsible of a posttranscriptional inhibitory activity partly unspecific due firstly to their possible direct negative action during translation by hybridizing that RNAs especially inside the mitochondrion, hence slowing the mitochondrial respiration, and secondly to the large number of their putative targets like in immune works or in cancer control. We will show that in each case the circuits in the core of the interaction graphs are responsible of a few number of dedicated attractors, responsible of the genetically controlled functions, this small amount of possible behaviours being partly due to the microRNA general braking.