• DocumentCode
    617421
  • Title

    A quadratic majorize-minimize framework for statistical estimation with noisy rician- and noncentral chi-distributed MR images

  • Author

    Varadarajan, Divya ; Haldar, Justin P.

  • Author_Institution
    Signal & Image Process. Inst., Univ. of Southern California, Los Angeles, CA, USA
  • fYear
    2013
  • fDate
    7-11 April 2013
  • Firstpage
    712
  • Lastpage
    715
  • Abstract
    The statistics of noisy MR magnitude and square-root sum-of-squares MR images are well-described by the Rice and noncentral chi distributions, respectively. Statistical estimation involving these distributions is complicated by the facts that they have first- and second-order moments that depend nonlinearly on the noiseless image, and can have nonconvex negative log-likelihoods. This paper proposes a new majorize-minimize framework to ease the computational burden associated with statistical estimation involving these distributions. We derive quadratic tangent majorants for the negative log-likelihoods, which enables statistical cost functions to be optimized using a sequence of much simpler least-squares or regularized least-squares surrogate problems. We demonstrate the use of this framework in the context of regularized MR image denoising, with both simulated and experimental data.
  • Keywords
    biomedical MRI; image denoising; image sequences; mean square error methods; medical image processing; minimisation; statistical analysis; MR image denoising; first-order moments; image sequence; noiseless image; noisy Rician MR image; noncentral chi-distributed MR image; nonconvex negative log-likelihoods; optimization; quadratic majorize-minimize framework; second-order moments; square-root sum-of-squares MR image; statistical cost functions; statistical estimation; Context; Estimation; Magnetic resonance imaging; Noise; Noise reduction; Rician channels; Magnetic Resonance Imaging; Majorize-Minimize Algorithms; Noncentral Chi Distribution; Rice Distribution; Statistical Estimation;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Imaging (ISBI), 2013 IEEE 10th International Symposium on
  • Conference_Location
    San Francisco, CA
  • ISSN
    1945-7928
  • Print_ISBN
    978-1-4673-6456-0
  • Type

    conf

  • DOI
    10.1109/ISBI.2013.6556574
  • Filename
    6556574