Title :
Subcellular near-field biomolecule sampling using a biosensor
Author :
Qi Xia ; Hughes, Ashley ; Raghu, Deepa ; Reeves, Mark
Author_Institution :
Dept. of Phys., George Washington Univ., Washington, DC, USA
Abstract :
As the initial experiments towards integrating the near-field ablation and a fiber-optic biosensor, we report the near-field ablation on Arabidopsis thaliana leaf samples with a 2μm ablation spot. We also report time-dependent spectral plots of detecting biomolecules in the ground Arabidopsis leaf solution. The sensitivity of detecting biomolecules with amino functional groups was improved by using a biosensor coated with a specific type of cross linkers.
Keywords :
biosensors; botany; cellular biophysics; fibre optic sensors; molecular biophysics; Arabidopsis thaliana leaf samples; amino functional groups; biomolecules; cross linkers; fiber-optic biosensor; near-field ablation; size 2 mum; subcellular near-field biomolecule sampling; time-dependent spectral plots; Biosensors; Laser ablation; Optical fiber couplers; Optical fiber sensors; Probes; Proteins; Arabidopsis thaliana; Near-field ablation; fiber-optic biosensor; subcellular level;
Conference_Titel :
Microsystems for Measurement and Instrumentation (MAMNA), 2013
Conference_Location :
Gaithersburg, MD
Print_ISBN :
978-1-4799-0221-7
DOI :
10.1109/MAMNA.2013.6557233
