A highly sensitive biosensor based on a 3D gold nanostructure modified screen-printed electrode for glucose detection

In this study, we investigated a simple glucose biosensor based on a 3D gold nanostructure modified screen-printed electrode. The 3D gold nanostructure was electrochemically fabricated on the working electrode of a commercially available screen-printed electrode using an aqua regia dissolved bulk gold solution as the precursor. Potassium ferricyanide and glucose oxidase were then sequentially coated onto the prepared nanostructure for glucose detection. Glucose detections illustrated that the proposed devices could perform a sensitivity of 71.12 μA mM^-1cm^-2 with a linear detection range from 0.27-5.6 mM. A fast response time of less than 2 s was observed. Moreover, only a 5mL of glucose specimen is required for the detection due to the incorporation of the commercially available screen-printed electrode.