• DocumentCode
    620013
  • Title

    Predicting protein structural classes with autoencoder neural networks

  • Author

    Liu Jian-wei ; Chi Guang-hui ; Liu Ze-yu ; Liu Yuan ; Li Hai-en ; Luo Xiong-lin

  • Author_Institution
    Res. Inst. of Autom., China Univ. of Pet., Beijing, China
  • fYear
    2013
  • fDate
    25-27 May 2013
  • Firstpage
    1894
  • Lastpage
    1899
  • Abstract
    Autoencoder neural networks was firstly introduced by G.E.Hinton to reduce the dimensionality of data.In this paper, we propose a new way to classify protein structural classes using autoencoder neural networks. The optimum configurations with respect to the size of hidden layers are identified. The problem of training a deep autoencoder for classifying protein structural classes is addressed. Stacked autoencoder is used for reducing the convergence time of training. We design a series of experiments to testify the effectiveness of using autoencoder networks to tackle the problem of predicting protein structure. The experimental results show that our proposed method is competitive with state-of-the-art SVM methods in predicting protein structure class.
  • Keywords
    biology computing; molecular biophysics; neural nets; pattern classification; proteins; autoencoder neural networks; convergence time reduction; data dimensionality reduction; deep autoencoder training problem; hidden layer size; optimum configuration identification; protein structural class classification; protein structural class prediction; stacked autoencoder; Amino acids; Error analysis; Mathematical model; Neural networks; Proteins; Support vector machines; Vectors; autoencoders network; protein structural class; pseudo amino acid model;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Control and Decision Conference (CCDC), 2013 25th Chinese
  • Conference_Location
    Guiyang
  • Print_ISBN
    978-1-4673-5533-9
  • Type

    conf

  • DOI
    10.1109/CCDC.2013.6561242
  • Filename
    6561242