DocumentCode
620013
Title
Predicting protein structural classes with autoencoder neural networks
Author
Liu Jian-wei ; Chi Guang-hui ; Liu Ze-yu ; Liu Yuan ; Li Hai-en ; Luo Xiong-lin
Author_Institution
Res. Inst. of Autom., China Univ. of Pet., Beijing, China
fYear
2013
fDate
25-27 May 2013
Firstpage
1894
Lastpage
1899
Abstract
Autoencoder neural networks was firstly introduced by G.E.Hinton to reduce the dimensionality of data.In this paper, we propose a new way to classify protein structural classes using autoencoder neural networks. The optimum configurations with respect to the size of hidden layers are identified. The problem of training a deep autoencoder for classifying protein structural classes is addressed. Stacked autoencoder is used for reducing the convergence time of training. We design a series of experiments to testify the effectiveness of using autoencoder networks to tackle the problem of predicting protein structure. The experimental results show that our proposed method is competitive with state-of-the-art SVM methods in predicting protein structure class.
Keywords
biology computing; molecular biophysics; neural nets; pattern classification; proteins; autoencoder neural networks; convergence time reduction; data dimensionality reduction; deep autoencoder training problem; hidden layer size; optimum configuration identification; protein structural class classification; protein structural class prediction; stacked autoencoder; Amino acids; Error analysis; Mathematical model; Neural networks; Proteins; Support vector machines; Vectors; autoencoders network; protein structural class; pseudo amino acid model;
fLanguage
English
Publisher
ieee
Conference_Titel
Control and Decision Conference (CCDC), 2013 25th Chinese
Conference_Location
Guiyang
Print_ISBN
978-1-4673-5533-9
Type
conf
DOI
10.1109/CCDC.2013.6561242
Filename
6561242
Link To Document