A CMOS Analog Correlator-Based Painless Nonenzymatic Glucose Sensor Readout Circuit

Author

Shenoy, Varun ; Sungyong Jung ; Youngsam Yoon ; Youngjin Park ; Hyoungsoo Kim ; Hoon-Ju Chung

Author_Institution

Electr. Eng. Dept., Univ. of Texas at Arlington, Arlington, TX, USA

Volume

14

Issue

5

fYear

2014

fDate

May-14

Firstpage

1591

Lastpage

1599

Abstract

An analog correlator-based readout circuit for amperometric glucose electrochemical biosensors is designed and implemented in 0.35- μm CMOS process. The readout circuit offers lower noise and wider dynamic range compared with the conventional transimpedance amplifier architecture. The operational amplifier achieves a 118.3-dB gain and 47.3 ° phase margin. The readout circuit dc response for input range of 5-30 μA gives a linear output voltage range of 0.21-1.38 V. The total output rms noise is measured to be 6.6 m Vrms. It is applied for a microneedle glucose sensor and has a mean error of 1.6% and consumes 5.1 mW of power. The total area of the proposed readout circuit is 300 μm× 167 μm.

Keywords

CMOS analogue integrated circuits; amperometric sensors; biosensors; correlators; operational amplifiers; readout electronics; sugar; CMOS analog correlator; amperometric glucose electrochemical biosensors; current 5 muA to 30 muA; dc response; dynamic range; noise; operational amplifier; painless nonenzymatic glucose sensor readout circuit; phase margin; power 5.1 mW; size 0.35 mum; total area; voltage 0.21 V to 1.38 V; Blood; Correlators; Current measurement; Electrodes; Noise; Sensors; Sugar; CMOS; Glucose sensor; amperometric circuit; correlator; microneedle; readout circuit;

fLanguage

English

Journal_Title

Sensors Journal, IEEE

Publisher

ieee

ISSN

1530-437X

Type

jour

DOI

10.1109/JSEN.2014.2300475

Filename

6714377